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Instructions of NURS-6521 Advanced Pharmacology W9
Week 9 Case Studies
1 SectionAdvanced Pharmacology-Spring 2024
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Directions: For each of the scenarios below, answer the questions below using clinical
practice guideline where applicable. Explain the problem and explain how you would
address the problem. If prescribing a new drug, write out a complete medication order
just as you would if you were completing a prescription. Use at least 3 sources for each
scenario and cite sources using APA format.
Jamie is a 38-year-old homeless bipolar patient that is diagnosed with an acute
psychotic episode. He tells you that he has been on lithium for years and was
recently started on amitriptyline (Elavil) 25mg po TID by someone at a free clinic.
What treatment plan would you develop to Jamie? Would you discontinue any
medications? What medications would you add?
A 68-year-old woman has a history of rheumatoid arthritis and has been taking
nabumetone (Relafen) 1000 mg po qd for 2 years. Other pertinent past medical
history includes: occasional incontinence, Crohn’s disease with frequent
exacerbations, and well-controlled diabetes type 2. Recently, her arthritis pain
has been much worse and she is requesting additional medication for her
rheumatoid arthritis. What would be appropriate additional therapy for this
patient? What monitoring would be appropriate to monitor this medication? What
monitoring would be appropriate to monitor this medication?- Sheila is a 26-year-old with history of head injury and tonic clonic seizures. She
is seen today with complaints of “funny” eye movements, feeling uncoordinated,
blurred vision, and feeling lethargic. Her current medications include Ritalin 10
mg po BID, Dilantin 300 mg po BID, Paxil 20 mg po daily, Lasix 20 po daily Lab
Values from today Dilantin level of 11 Albumin 2 WBC 9.9 Plt 177 Na 141 K 4.2
Hg 13.2. What do you think is causing the patient’s symptoms? What lab values
and calculated corrected medication level support your diagnosis? What is your
treatment plan for this patient?
Xavi is a 44-year-old man with complaints of low back pain following a motor
vehicle accident. The accident occurred 7 days ago. He rates his pain 8 out of
10. He was prescribed Lortab 5 / 325 in the ER last week. He is requesting a refill
of the Lortab today and indicates it just barely makes him comfortable. What
treatment plan would you implement for Xavi? What medications would you
prescribe and how would you monitor them? What education would you provide
regarding his treatment plan?
ASSIGNMENT: CASE STUDIES
Case studies are a useful way for you to apply your knowledge of pharmacokinetics and pharmacodynamic aspects of pharmacology to specific patient cases and health histories.
For this Assignment, you evaluate drug treatment plans for patients with various disorders and justify drug therapy plans based on patient history and diagnosis.
RESOURCES
Be sure to review the Learning Resources before completing this activity.
Click the weekly resources link to access the resources.
To Prepare:
- Review the case study posted in “Announcements” by your Instructor for this Assignment
- Review the information provided and answer questions posed in the case study
- When recommending a medication, write out a complete prescription for the medication
- Whenever possible, use clinical practice guidelines in developing your answers when possible
- Include at least three references to support your answer and cite them in APA format.
BY DAY 7 OF WEEK 9
Submit the Assignment.
SUBMISSION INFORMATION
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- To submit your completed assignment, save your Assignment as WK9Assgn_LastName_Firstinitial
- Then, click on Start Assignment near the top of the page.
Next, click on Upload File and select Submit Assignment for review.
Step-By-Step Guide NURS-6521 Advanced Pharmacology W9: Women’s and Men’s Health Assignment: Case Studies
Introduction to NURS-6521 Week1: ASSIGNMENT: Case Studies
Welcome to NURS-6521 Advanced Pharmacology W9: Women’s and Men’s Health Assignment: Case Studies. This assignment focuses on applying your knowledge of pharmacokinetics and pharmacodynamics to specific patient cases related to women’s and men’s health, and ear, eyes, and skin disorders. Through these case studies, you will evaluate and justify drug treatment plans based on patient history and diagnosis. This NURS-6521 guide provides step-by-step instructions to help you successfully complete each scenario.
Jamie is a 38-year-old homeless bipolar patient diagnosed with an acute psychotic episode. He has been on lithium for years and was recently started on amitriptyline (Elavil) 25 mg PO TID by someone at a free clinic. What treatment plan would you develop for Jamie?
Jamie’s Acute Psychotic Episode Management
- Maintain lithium for mood stabilization.
- Discontinue amitriptyline due to its potential to exacerbate psychosis and its interactions with lithium.
- Consider adding an antipsychotic, such as risperidone 1 mg BID, to manage the acute psychotic episode.
- Monitor serum lithium levels regularly to avoid toxicity.
- Discuss the importance of medication adherence, potential side effects, and the need for regular follow-up appointments.
Example
Jamie, a 38-year-old homeless bipolar patient, is experiencing an acute psychotic episode and is currently on lithium. Recently, he was started on amitriptyline (Elavil) 25 mg PO TID. The combination of lithium and amitriptyline can increase the risk of lithium toxicity and exacerbate psychotic symptoms. Therefore, the first step is to discontinue amitriptyline due to its potential for causing adverse interactions and worsening Jamie’s condition.
A 68-year-old woman with a history of rheumatoid arthritis and other comorbidities is requesting additional medication for worsening arthritis pain. What additional therapy would you implement? How would you monitor the new medication?
68-Year-Old Woman’s Rheumatoid Arthritis Management
- Consider adding a disease-modifying antirheumatic drug (DMARD) such as methotrexate 7.5 mg once weekly.
- Assess for contraindications and drug interactions with her current medications.
- Regularly monitor liver function tests and complete blood counts.
- Schedule follow-up visits every 3 months to assess efficacy and side effects.
- Inform the patient about potential side effects of methotrexate and the importance of regular monitoring.
Example
A 68-year-old woman with a history of rheumatoid arthritis (RA) and comorbid conditions, including Crohn’s disease and well-controlled type 2 diabetes, is experiencing increased arthritis pain despite being on nabumetone 1000 mg PO daily. Given her worsening symptoms, adding a disease-modifying antirheumatic drug (DMARD) is appropriate. Methotrexate, starting at 7.5 mg once weekly, is a suitable option for RA management.
Sheila, a 26-year-old with a history of head injury and tonic-clonic seizures, presents with symptoms suggestive of medication side effects. What is causing her symptoms? What lab values support your diagnosis? What is your treatment plan?
Sheila’s Seizure Management
- Suspect Dilantin toxicity given her symptoms and low albumin level.
- Calculate corrected Dilantin level considering her albumin.
- Dilantin level of 11 and albumin of 2 suggest a higher effective level due to low protein binding.
- Corrected Dilantin level = measured level / (0.2 × albumin + 0.1).
- Reduce Dilantin dose to avoid toxicity and re-evaluate after a week.
- Monitor Dilantin levels and symptoms closely.
Example
Sheila, a 26-year-old with a history of head injury and tonic-clonic seizures, presents with symptoms suggestive of Dilantin (phenytoin) toxicity, including “funny” eye movements, uncoordinated feeling, blurred vision, and lethargy. Her current medications include Ritalin 10 mg BID, Dilantin 300 mg BID, Paxil 20 mg daily, and Lasix 20 mg daily. Her lab results show a Dilantin level of 11 and albumin of 2, indicating a need to calculate the corrected Dilantin level.
Xavi, a 44-year-old man, presents with severe low back pain following a motor vehicle accident. He requests a refill of Lortab 5/325. What treatment plan would you implement? What medications would you prescribe and how would you monitor them?
Xavi’s Low Back Pain Management
- Address pain management with a combination approach.
- Continue Lortab 5/325 as needed but consider adding non-opioid pain management options.
- Prescribe ibuprofen 400 mg TID as an anti-inflammatory.
- Consider a muscle relaxant such as cyclobenzaprine 10 mg TID if muscle spasms are present.
- Schedule follow-up visits to reassess pain levels and medication effectiveness.
- Educate Xavi on the risks of opioid dependence and encourage non-pharmacological pain management strategies such as physical therapy.
Example
Xavi, a 44-year-old man with severe low back pain following a motor vehicle accident, rates his pain as 8 out of 10. He was prescribed Lortab 5/325 in the ER last week and requests a refill. Given the acute nature of his pain and the high pain rating, it is appropriate to continue opioid analgesics while also incorporating non-opioid pain management strategies.
Continue Lortab 5/325 every 6 hours as needed for pain but add ibuprofen 400 mg TID to address inflammation.
Closing
In this NURS-6521 Advanced Pharmacology W9: Women’s and Men’s Health Assignment: Case Studies, you will enhance your understanding of pharmacokinetics and pharmacodynamics by evaluating drug treatment plans for various patient scenarios. By following these Owlisdom guidelines, you can effectively address each patient’s needs, prescribe appropriate medications, and ensure thorough monitoring of treatment plans. This practice will help solidify your clinical decision-making skills and improve patient outcomes in managing women’s and men’s health, and ear, eyes, and skin disorders. In the next module of NURS-6521, we will discuss Advanced Pharmacology Week 10: Infection.